An in-depth understanding of human physiology, disease, and treatment is critical in developing innovative medical tools. At the DNA Medicine Institute, the translation between cutting edge technology and real-world applications is intuitive. There is nothing being developed at the Institute that lacks the direct potential to impact lives and patient care.
Nanomedicine is the application of nanotechnology to solve key problems in disease treatment and diagnosis. Nanotechnology deals with objects that are a billionth of a meter. Tiny technologies are required to deal with life's malfunctions, which occur on these scales. Using the latest advances in this field, we are creating new dimensions of how diseases can be controlled.
With the explosion of genetic data in the recent decade, and with the completed Human Genome Project, ample opportunity exists for development of new applications for understanding and studying genome function. Our staff has significant expertise in developing technologies that further our understanding of DNA, including its sequence, function, identification, and analysis.
Utilizing state-of-art optical, mechanical, and software engineering tools, we have developed the ability to rapidly prototype ideas to completed parts and products in record time. The key to our efficiency is leveraging off the best CAD/CAM tools, machining equipment, and latest advances in prototyping to help us reduce the cycle time required for testing ideas.
Biomedical engineering is the design, development, and testing of apparatuses and technology for the advancement of biological systems. By itself, it is interdisciplinary and integrative. It brings together a breadth of engineering disciplines to study problems that otherwise cannot be tackled with traditional biological or medical approaches.
Microfluidics is the science of manipulating fluid in channels that are on the micron, or one-millionth of a meter, scale. Performing laboratory procedures and tests at these scales allows for significant increases in speed and versatility. We have developed innovations in rapid prototyping, microfluidic mixing, and sample handling that speed the time of biological and chemical analyses.
Single Molecule Detection
A single molecule is invisible to the naked eye and almost impossible to detect under a microscope. While approximately ten million biomolecules can fit on the head of a pin, the presence of just one abnormal molecule can mean the presence of disease. We have adapted technology utilized for finding faint distant stars for microscopy and the measurement of individual molecules. This capability allows more sensitive diagnostics and tests to be performed.
Physics & Biophysics
Proteins, DNA, and other molecules inside our bodies are intricate molecular machines that perform extremely delicate procedures in a synchronized manner. The ultra-fine movements of molecules can govern the function of an entire cell or even organism. For example, in cystic fibrosis, a mutation in one ion channel protein causes defective chloride transport and thus disease. Understanding and controlling the basic molecular physics of these molecules is one of our core specialties.